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Type 2 Diabetes Clinical Trials in Santa Ana, CA
A listing of 4 Type 2 Diabetes clinical trials in Santa Ana, CA actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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The city of Santa Ana, California, currently has 4 active clinical trials seeking participants for Type 2 Diabetes research studies.
Featured Trial
New High Blood Pressure (Hypertension) Clinical Trials
Recruiting
This campaign features 7 hypertension studies for adults with high blood pressure that remains uncontrolled despite medication. Studies are available for a range of cardiovascular profiles, including people taking multiple blood pressure medications or living with heart or vascular disease.
Inclusion Criteria:
- Diagnosed with high blood pressure (hypertension)
- Age 18+ (one study requires participants to be 55+)
- Blood pressure remains elevated despite taking medication (typically systolic 135 mmHg or higher), or your doctor has expressed concerns about your blood pressure
- Currently taking 2 or more blood pressure medications
- Have cardiovascular disease (such as a previous heart attack, coronary artery disease, stroke, or peripheral artery disease) or certain cardiovascular risk factors, including diabetes, chronic kidney disease (CKD), atrial fibrillation (AF), or smoking (study dependent)
- Stable body weight for the past 3 months
Find out if you qualify today.
Inclusion Criteria:
- Diagnosed with high blood pressure (hypertension)
- Age 18+ (one study requires participants to be 55+)
- Blood pressure remains elevated despite taking medication (typically systolic 135 mmHg or higher), or your doctor has expressed concerns about your blood pressure
- Currently taking 2 or more blood pressure medications
- Have cardiovascular disease (such as a previous heart attack, coronary artery disease, stroke, or peripheral artery disease) or certain cardiovascular risk factors, including diabetes, chronic kidney disease (CKD), atrial fibrillation (AF), or smoking (study dependent)
- Stable body weight for the past 3 months
Find out if you qualify today.
Conditions:
Hypertension Multi
Hypertension
Pulmonary Hypertension
Ocular Hypertension
Pulmonary Arterial Hypertension
Featured Trial
New Obesity Clinical Studies Now Recruiting
Recruiting
We are seeking participants for multiple clinical trials focused on obesity and metabolic health, evaluating investigational treatments for weight management and diabetes. Studies are looking for adults with obesity, with or without type 2 diabetes, who are not currently taking GLP-1 medications or other weight-loss treatments.
See if you qualify today.
See if you qualify today.
Conditions:
Obesity Multi
Obesity
Overweight and Obesity
Morbid Obesity
Childhood Obesity
Featured Trial
Multiple Type 2 Diabetes Studies Now Recruiting
Recruiting
We are seeking participants for 14 clinical studies investigating new treatments for type 2 diabetes (T2DM) and related conditions including obesity and fatty liver disease (MASH/NAFLD). Studies are looking for adults with a confirmed T2DM diagnosis who are not well-controlled or are seeking improved management, spanning a range of disease stages from early/diet-managed to long-standing and multiply medicated.
See if you qualify today.
See if you qualify today.
Conditions:
Type 2 Diabetes Multi
Type 2 Diabetes
Diabete Type 2
Diabetic Nephropathy Type 2
Type 2 Diabetes Mellitus
Featured Trial
Reduce Heart Failure Risk – See if You Qualify for a Study
Recruiting
We are currently looking for individuals aged 18 and older to take part in a heart disease research study. You may be eligible if you have been diagnosed with all of the following:
• Cardiovascular Disease
• Type 2 Diabetes
• High Blood Pressure
This study is exploring an investigational medication that may help reduce the risk of heart-related complications.
If you’re interested in learning more, you can see if you pre-qualify today.
• Cardiovascular Disease
• Type 2 Diabetes
• High Blood Pressure
This study is exploring an investigational medication that may help reduce the risk of heart-related complications.
If you’re interested in learning more, you can see if you pre-qualify today.
Conditions:
Heart Diseases
Congenital Heart Disease
Coronary Heart Disease
Ischemic Heart Disease
Heart Disease
Featured Trial
Now Recruiting: Cardiovascular Disease (CVD) Clinical Studies
Recruiting
We are seeking participants for 31 cardiovascular disease (CVD) studies covering conditions such as high blood pressure (hypertension), atherosclerotic heart disease, high cholesterol (hyperlipidemia), heart failure, and type 2 diabetes with CVD. The studies are recruiting adults ages 18 and older who have been diagnosed with one or more of these conditions and are currently receiving treatment.
See if you qualify today.
See if you qualify today.
Conditions:
CVD Multi
CVD
Cardiovascular Disease
Cardiovascular Diseases
High Blood Pressure
Featured Therapy
Unique Treatment for High Blood Pressure
Worried about high blood pressure? Think beyond typical high blood pressure treatments.
People who may be candidates for this procedure:
• Are at least 18 years old
• Have been unable to manage their high blood pressure with medications or lifestyle changes alone¹
Learn about a safe and effective procedure that may help reduce high blood pressure. See if you qualify today.
¹ Kandzari DE, et al. J Am Coll Cardiol. Nov 7, 2023;82(19):1809-1823.
People who may be candidates for this procedure:
• Are at least 18 years old
• Have been unable to manage their high blood pressure with medications or lifestyle changes alone¹
Learn about a safe and effective procedure that may help reduce high blood pressure. See if you qualify today.
¹ Kandzari DE, et al. J Am Coll Cardiol. Nov 7, 2023;82(19):1809-1823.
Conditions:
High Blood Pressure
High Blood Pressure (& [Essential Hypertension])
High Blood Pressure (Hypertension).
Hypertension
Essential Hypertension
A Research Study Comparing How Well Different Doses of the Medicine NNC0487-0111 Lower Blood Sugar in People With Type 2 Diabetes
Recruiting
The study will look at how well different doses of a new medicine called NNC0487-0111 help lower the blood sugar and body weight in people with type 2 diabetes. NNC0487-0111 is a new medicine which cannot be prescribed by doctors but has previously been tested in humans. Participants will either get NNC0487-0111, which is given as tablets or as injections, or placebo. Which treatment the participant get is decided by chance.The study will last for about 43 weeks.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/10/2025
Locations: Southern Cal Clinical Research, Santa Ana, California
Conditions: Type 2 Diabetes (T2D)
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 Diabetes
Recruiting
The main purpose of this study is to see how orforglipron, compared with placebo, helps improve glycemic control in participants with obesity or with overweight and type 2 diabetes. This trial is part of the master protocol study J2A-MC-GZPO.
Participation in the study will last about 18 months.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2025
Locations: Southern California Clinical Research, Santa Ana, California
Conditions: Obesity, Overweight, Type 2 Diabetes
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Recruiting
The purpose of this study is to measure the change in hemoglobin A1c (HbA1c) with LY3457263 compared with placebo in participants with type 2 diabetes who are not at HbA1c goal when treated with a stable dose of semaglutide or tirzepatide. Participation in the study will last about 9 months.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
07/01/2025
Locations: Wolverine Clinical Trials, Santa Ana, California
Conditions: Type 2 Diabetes
A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 Diabetes
Recruiting
The purpose of this Master Protocol is to support two studies to see how well and how safely orforglipron works compared to placebo in participants who have obesity or overweight with or without type 2 diabetes. Participants will be screened for about 4 weeks, after which they will enroll into either J2A-MC-GZP1, NCT06972459 (do not have type 2 diabetes) or J2A-MC-GZP2, NCT06972472 (have type 2 diabetes).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/24/2025
Locations: Southern California Clinical Research, Santa Ana, California
Conditions: Obesity, Overweight, Type 2 Diabetes
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